Dental Informatics and Dental Research   Conference, June 12-13, 2003: Making the Connection
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Conference Attendee - Details

Abdullah Karadag, MD, PhD, MSc

akaradag@dir.nidcr.nih.gov

Research Fellow

National Institutes of Health

(see )

Research Interests:
  • Bone
  • Cancer
  • Bioinformatics
  • SIBLINGs
  • Bone sialoprotein
  • Osteopontin
  • DMP1
  • DSPP
  • MEPE
  • MMP
  • Integrin
  • Invasion
Current Projects:

Regulation of tumor invasion through interactions between BSP, MMP-2 and integrins.

Usage of PNA hybridization probes and FRET technique to quantify mutation rate in McCune Albright Syndrome by application of Real time PCR.

Selected Publications:

Jain A., Karadag A., Fohr B., Fisher L.W., Fedarko N.S. Three SIBLINGs (Small Integrin-Binding LIgand, N-linked Glycoproteins) Enhance Factor H's Cofactor Activity Enabling MCP-like Cellular Evasion of Complement-mediated Attack. Journal of Biological Chemistry, 277, 13700-13708, 2002.

Fedarko N.S., Jain A., Karadag A., Van Eman M., Fisher L.W. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate and lung cancer. Clinical Cancer Research, 7(12), 4060-4066, 2001.

Karadag A., Scutt A.M., Croucher P.I. Myeloma cells promote the recruitment of osteoblast precursors in vitro: mediation by interleukin-6 (IL-6) and the soluble IL-6 receptor (sIL-6R). Journal of Bone and Mineral Research, 15(10), 1935-1943, 2000.

Karadag A., Oyajobi B.O., Apperley J.F., Russell R.G.G., Croucher P.I. Human myeloma cells promote the production of interleukin 6 by primary human osteoblasts British Journal of Haematology, 108(2), 383-390, 2000.

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